Resolution of renal allograft-associated post-transplant lymphoproliferative disorder with the introduction of sirolimus
نویسندگان
چکیده
منابع مشابه
Resolution of renal allograft-associated post-transplant lymphoproliferative disorder with the introduction of sirolimus.
Lymphoid neoplasia has remained a serious complication following solid organ transplantation. Recent data suggest an 11.8-fold higher risk of lymphoma compared with the general population over a 10 year period [1]. Although the risk is greatest within the first year posttransplant, the incidence remains high throughout the entire post-transplant period. Risk factors include unrestrained prolife...
متن کاملPost-transplant lymphoproliferative disorder.
BACKGROUND Posttransplant lymphoproliferative disorder (PTLD) is increasingly recognized as a serious complication of solid organ transplantation in both children and adults. Factors associated with increased risk of PTLD include mismatch of recipient and donor EBV serologic status (seronegative recipient with seropositive donor), and intensive drug-induced immunosuppression. METHODS AND RESU...
متن کاملOcular post-transplant lymphoproliferative disorder
We report a case of an iris tumor with muttonfat keratic precipitates in a young patient after liver transplantation surgery. A 6yearold girl underwent liver transplantation for congenital biliary atresia and was subsequently immunosuppressed with oral cyclosporine. We examined her 5 years after transplantation because of a "white nodule in her left eye," which had been detected by her father o...
متن کاملRapidly progressive post-transplant lymphoproliferative disease following withdrawal of sirolimus.
Sirolimus, a potent inhibitor of B- and T-cell activation. is a commonly used immunosuppressant after renal transplantation. Withdrawal of sirolimus from the immunosuppression regimen may reduce B-cell surveillance. We present a case of rapidly progressive central nervous system (CNS) polymorphic Epstein-Barr virus (EBV)-related post-transplant lymphoproliferative disorder following the withdra...
متن کاملEpstein-Barr virus-associated post-transplant lymphoproliferative disorder.
We describe a patient that developed Epstein-Barr virus (EBV)-associated post-transplant lymphoproliferative disorders (PTLD), which presented as interstitial pneumonia. He had received allogeneic bone marrow transplantation for the treatment of acute myeloid leukemia 17 months before, when he developed hypoxemia requiring emergent admission. Chest computed tomography revealed pulmonary interst...
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2005
ISSN: 1460-2385,0931-0509
DOI: 10.1093/ndt/gfh884